Automated Online Sample Preparation Comes to Waters
UltraPerformance Liquid Chromatography (UPLC) Platform
MILFORD, Mass., Nov. 20,
2012 /PRNewswire/ -- Waters Corporation (NYSE:WAT) announced
today that its ACQUITY UPLC® System is now available
with online solid phase extraction (SPE) technology from Spark
Holland BV (Emmen, The
Netherlands). The Waters® ACQUITY UPLC
Online SPE Manager is based on a special version of the
highly-popular Spark Holland online SPE technology, which Spark
Holland is making available to Waters exclusively. The Waters
ACQUITY UPLC Online SPE Manager is now available as an integrated
Waters UPLC/MS system or as an upgrade to installed ACQUITY UPLC
Systems under an agreement with Spark Holland. High-throughput
analytical laboratories can now streamline sample preparation and
analysis time and generate test results faster than before. The
integrated system is sold and supported by Waters worldwide.
(Logo:
http://photos.prnewswire.com/prnh/20110707/NE31586LOGO )
"Combining our UPLC technology with Spark Holland's online SPE
technology offers compelling benefits to high-throughput
laboratories intent on producing the highest-quality test results,
quickly and reproducibly for UPLC/MS analyses," said Ian King, Vice President, Separations
Technologies, Waters Division. "Automating the process of sample
preparation can help laboratories greatly improve turnaround times,
reduce errors and the control costs."
"Coupling online SPE to UPLC efficiently, while maintaining the
unique benefit of disposable SPE cartridges, is a major
technological challenge that performs best in a completely
integrated fashion," said Rob van der
Knaap, President, Spark Holland. "Integration of our online
SPE technology with the ACQUITY UPLC System creates a superior
platform for completely automated SPE-UPLC based analyses."
Leading laboratories use Spark Holland automated sample
preparation devices to streamline sample preparation and analysis
for routine, high throughput applications. Scientists employ online
solid phase extraction when removing involatile salts, ion
suppressing species and other interferences from samples prior to
analysis. This reduces analysis time, reduces errors caused by
manual SPE procedures, as well as provides a significant
improvement in selectivity and concentrates analytes for better
sensitivity. Covance Inc., one of the world's largest drug
development services companies, employs automated online SPE and
reports that it frequently allows quantification of even very large
peptides down to the 10 pg/mL level in human
plasma.1
In 2007, Waters and Spark Holland announced the availability of
the Waters Oasis® brand sorbent line for a
newly-designed Spark Holland 800-series format tray for the Spark
Holland® Symbiosis™ and Prospekt-2™ systems. For the new
system special UPLC® cartridges are offered as well as
novel applications. Spark Holland
intends to expand its cartridge product line and applications
portfolio continuously to serve clinical, pharmaceutical, food
safety, and environmental control laboratories.
About Spark Holland (www.sparkholland.com)
Spark Holland has more than 30
years of history in HPLC and UHPLC instrument innovation,
specializing in the field of autosampling and online solid phase
extraction and, more recently, online dried blood spot analysis.
Today, Spark Holland is a leading OEM supplier of front-end UHPLC
and online solid phase extraction instruments, working according to
ISO 13485 and, when required, delivering CE-IVD compliant
modules for use in clinical systems. Spark Holland is a privately held firm with
operations based in Emmen, The
Netherlands.
About Waters Corporation (www.waters.com)
For over 50 years, Waters Corporation has created business
advantages for laboratory-dependent organizations by delivering
practical and sustainable innovation to enable significant
advancements in such areas as healthcare delivery, environmental
management, food safety, and water quality worldwide.
Pioneering a connected portfolio of separations science,
laboratory information management, mass spectrometry and thermal
analysis, Waters technology breakthroughs and laboratory solutions
provide an enduring platform for customer success.
With revenue of $1.85 billion in
2011, Waters is driving scientific discovery and operational
excellence for customers worldwide.
1. Bioanalytical
Approaches to Analyzing Peptides and Proteins by
LC/LC- MS, Bioanalysis (2011)
3(12), 1379-1397
Waters, Oasis, UPLC, and ACQUITY UPLC are registered trademarks
of Waters Corporation.
Spark Holland, Symbiosis, and
Prospekt are trademarks of Spark-Holland BV.
SOURCE Waters Corporation