NEW YORK, Nov. 29, 2012 /PRNewswire/ -- Reportlinker.com
announces that a new market research report is available in its
catalogue:
KOL Insight: Hepatitis C: the race for the first
interferon-free regimen
http://www.reportlinker.com/p01048198/KOL-Insight-Hepatitis-C-the-race-for-the-first-interferon-free-regimen.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Pathology
Analyzing the Hepatitis C Market Landscape
After more than a decade of limited treatment options, the
hepatitis C (HCV) market is on the cusp of a treatment revolution.
In 2011, protease inhibitors-Incivek (telaprevir; Vertex) and
Victrelis (boceprevir; Merck)-became the first new drugs approved
in the disease in over a decade; however after a bright start sales
have plateaued as treatment is held back in less severe
populations. Key opinion leaders cite this 'warehousing' effect is
due to the anticipated arrival of the more convenient, efficacious
and safer therapies. Pipeline combinations led by Gilead,
Abbott, Bristol-Myers Squibb and
Boehringer Ingelheim all have favourable clinical results and
notably are not used in conjunction with pegylated-interferon
alpha, a key component in the current standard of care but
associated with tolerability issues. The battle to be the first
will be intense as availability of a non-interferon regimen will
transform this potentially lucrative market.
'Therapy Trends: Hepatitis C' is compiled from exclusive,
in-depth interviews with the world's leading KOLs in HCV. It
identifies and analyses the major factors, advances and trends
currently influencing the HCV treatment landscape. The report
focuses on late-stage pipeline products, and how these could modify
future HCV management.
FirstWord selected KOLs to participate in this Therapy Trends
research based on their level of engagement and influence within
the HCV pharmaceutical industry, and their scientific standing. Our
unique KOL scoring system identifies those thought-leaders with the
greatest insight into how HCV clinical research will shape the
future market.
Key Benefits
Hepatitis C: the race for the first interferon-free regimen
examines the most prominent insights gained from the field's key
opinion leaders. The results of FirstWord's research and analysis
will help you to:
Comprehend the current trends driving and shaping the global HCV
market
Understand the future landscape and how new classes will fit
into the treatment algorithm
Assess the commercial and clinical potential of the pipeline
nucs, non-nucs, NS5A inhibitors and next generation protease
inhibitors
Develop planning strategies based on insight from the field's
foremost KOLs
Identify the unmet needs and opportunities for disease
management
Evaluate the potential of companies with the most promising new
product pipelines
Recognise the key factors KOLs predict will drive future
treatment trends
Critical Questions Answered
Understand the Global Hepatitis C Market
The hepatitis C (HCV) market is expected to become one of the
fastest growing markets in Pharma over the next decade given a
sizable 170 million patient population, a significant unmet need
and rapid advancements in the clinic. The management of this
infectious disease is on the verge of a revolution that will bring
considerable changes to the treatment algorithm. KOLs from
North America and Europe provide answers to the critical
questions regarding the global HCV market, including:
What do KOLs make of the Incivek and Victrelis and their impact
on treatment?
What are the current unmet needs and major challenges in HCV
treatment?
What are the most promising late-stage classes in
development?
Which therapy are KOLs eagerly awaiting?
How will the nucleotide inhibitors, non-nucs, and NS5A
inhibitors be positioned in the HCV market?
How do the second generation protease inhibitors differ from
their first-generation cousins?
In what ways could eventual biomarkers improve future HCV
disease management?
How will treatment of HCV look in the future?
How do KOLs think the pricing environment will shape the uptake
of new HCV treatments?
What clinical research trends do KOLs predict for future HCV
therapies?
KOL Panel
FirstWord selected the KOLs for this Therapy Trends report based
on their level of engagement and influence within the HCV
pharmaceutical industry, and their scientific standing. The HCV KOL
panel assembled for this Therapy Trends research is drawn from
North American and European professionals:
Adult Viral Hepatitis Prevention Coordinator, Bureau of
Epidemiology, Pennsylvania Department of Health, Harrisburg, PA, USA
Director of Hepatology, Medicine Service, Massachusetts General
Hospital, MA, US
President and Medical Director at Alamo Medical Research,
Texas, US
Head, Division of Gastroenterology and Hepatology, Scripps
Clinic, CA, US
Chief Medical Officer at Alamo Medical Research Texas, US
Head of the Liver Institute of Virginia, Virginia, US
Department of Hépato-Gastroenterologie, Centre Hospitalier
Universitaire de Nancy-Brabois, Vandoeuvre-lès-Nancy, France
Professor of Medicine at the University of Vienna, Vienna General Hospital, Wien, Austria
Professor at Hôpital Saint Eloi, Montpellier, France
Co-lead of HCV Research UK, MRC Virology Unit, Glasgow, Scotland
Professor of Medicine and Chief of the Department of Medicine,
J.W. Goethe University Hospital,
Frankfurt, Germany
Event Assessments
Qualitative Analysis Update Within Days of Major Market
Events
Stay a step ahead with Therapy Trends Event Assessments. Over
the next 12 months, you will receive updated qualitative analysis
every time a major market event breaks. Updates will be delivered
straight into your inbox within days of each event's
occurrence.
Whether it's a predicted product approval or an unexpected late
stage failure, Therapy Trends has the resources and knowledge to
keep you up to date with the latest market analysis.
Methodology
An approach backed by unrivalled knowledge
This report provides a qualitative assessment of the current and
future Hepatitis C (HCV) market. Information was gathered from
in-depth telephone interviews with twelve key opinion leaders
(KOLs), from across the major HCV markets, including France, Germany, Italy, the UK and the US. These regions were
selected because they contain many of the largest global markets
for the pharmaceutical industry, and also dictate the dynamics of
Pharma markets in other countries.
In order to critically select Key Opinion Leaders (KOLs) a
number of parameters were considered including their clinical
experience, scientific publications, involvement with Pharma,
involvement in clinical trials, and record of presenting at high
profile international conferences.
Subject matter for discussion in the interviews covered future
diagnostic and therapeutic strategies for HCV, the future of HCV
drug classes, and new drugs entering the market. These leading KOLs
also gave their views on current research, the usefulness of
existing HCV drug classes, the cost of newer drugs and other
concerns in the therapy area.
Current Hepatitis C marketplace
Hepatitis C overview
Current treatment landscape
Reimbursement of key Hepatitis C brands
Unmet needs in Hepatitis C
Current therapies
Pivotal trial data of approved therapies
NS3/NS4A Protease inhibitor overview
Incivek/Incivo (telaprevir; Vertex's/Tibotec/Mitsubishi Tanabe)
trends
Victrelis (boceprevir; Merck) trends
Interferon and Ribavirin Overview
Pegylated interferon-alpha (Peg-Intron, PegaSys) and ribavirin
trends
Current treatment algorithm
Future Hepatitis C marketplace
Future treatment landscape
NS5B nucleoside (Nuc) inhibitors overview
Sofosbuvir (GS-7977, Gilead) trends
Mericitabine (RO5024048; Roche/Gilead) trends
Mericitabine (RO5024048; Roche/Gilead) trends
NS5B non-nucleoside inhibitor overview
BI-201127 (Boehringer Ingelheim) trends
ABT-333 (Abbott) trends
ABT-072 (Abbott) trends
VX-222 (Vertex) trends
Tegobuvir (GS-9190; Gilead) trends
NS5A replication complex inhibitor overview
Daclatasvir (BMS-790052; Bristol-Myers Squibb) trends
GS-5885 (Gilead Sciences) trends
ABT-267 (Abbott) trends
ACH-3102 (Achillion) trends
NS3/NS4A protease inhibitor overview
Faldaprevir (BI-201335; Boehringer Ingelheim) trends
ABT-450 (Abbott/Enanta)
trends
Asunaprevir (BMS-650032; Bristol-Myers Squibb) trends
Simeprevir (TMC435; Medivir/Tibotec) trends
Danoprevir (RO5190591; Roche) trends
Sovaprevir (ACH-1625; Achillion Pharmaceuticals) trends
Vaniprevir (MK-7009; Merck) trends
MK-5172 (Merck) trends
Future treatment algorithm
Future developments in Hepatitis C
Education to raise awareness and improve diagnosis
Clinical trials will evolve in the future
All-oral regimen will be approved by 2014
Constrained pricing environments will reduce market access
Effective shorter treatment regimes will emerge
Eventual development of biomarkers will aid treatment
To order this report:
Pathology Industry: KOL Insight: Hepatitis C: the race
for the first interferon-free regimen
Nicolas Bombourg
Reportlinker
Email: nicolasbombourg@reportlinker.com
US: (805)652-2626
Intl: +1 805-652-2626
SOURCE Reportlinker